منابع مشابه
Micronutrients and cancer.
Adverse dietary factors account for approximately 30% of all cancers. Overconsumption of energy is undoubtedly one of the major risk factors, but dietary composition is also very important. In particular, a low consumption of fruits and vegetables appears to double the risk of carcinomas of the lung and alimentary tract. Epidemiological studies suggest that high plasma levels of Se, carotenoids...
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Cancer cells exhibit altered glucose metabolism, mitochondrial dysfunction, anaerobic glycolysis and upregulation of the pentose phosphate pathway (PPP). Recent genetic and metabolic analyses have provided insights into the molecular mechanisms of genes that are involved in the alteration of cancer metabolism and tumorigenesis. Hypoxic induced factor 1 regulates the reciprocal relationship betw...
متن کاملMicronutrients and ovarian cancer: a case-control study in Italy.
BACKGROUND The role of selected micronutrients, vitamins and minerals in the aetiology of epithelial ovarian cancer was investigated using data from a case-control study conducted between 1992 and 1999 in five Italian areas. PATIENTS AND METHODS Cases were 1,031 patients with histologically confirmed incident epithelial ovarian cancer. Controls were 2,411 subjects admitted for acute, non-neop...
متن کاملGastrointestinal Cancer
Learning Objectives After completing this course, the reader will be able to: 1. Discuss the epidemiology of esophageal cancer. 2. Explain the current status of diagosing and treating esophageal cancer. 3. Describe potential novel targets for new drug development in esophageal cancer. Abstract Esophageal cancer is a highly aggressive neoplasm. In 2005, 14,520 Americans will be diagnosed with es...
متن کاملGastrointestinal Cancer
Colorectal cancer (CRC) is a major public health problem (1,200,000 new cases per year worldwide) and increasingly affects older people; the current median age at diagnosis is 71, and for CRC-related death is 75 years. After 50 years of age, the incidence doubles every seven years, and 76% of patients with newly diagnosed CRC are between 65 and 85 years of age. The liver is the most common site...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1993
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1993.503